Researchers at the Francis Crick Institute have found a new way to prevent some tumors from repairing their own DNA, a function that is essential for cancer cell survival. This discovery could lead to much needed new treatments ...
Dec 16, 2020
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More than 7% of human oocytes contain at least one exchangeless chromosome pair, demonstrating a remarkably high level of meiotic recombination failure, finds a study appearing December 10 in the American Journal of Human ...
Dec 10, 2020
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Treatments that harness the immune system to fight cancer have greatly improved outcomes for some people with cancer. Scientists are learning more about why some people respond much better than others to these drugs.
Dec 1, 2020
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New insights into the mechanisms behind how cancer-causing agents in the environment activate genetic recombination in DNA could help to explain some of the effects of exposure as well as predicting which individuals may ...
Nov 17, 2020
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Studies regarding the brain damage caused by the Zika virus have revealed the virus' predilection for a certain neural cell: the astrocyte. However, few studies have sought to identify the infection effects on these cells, ...
Jan 27, 2020
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A team of researchers at Boston Children's Hospital has learned more about the process of V(D)J recombination and how it makes use of chromatin looping to collect segments that are to be spliced. In their paper published ...
Researchers at the George Washington University (GW) Cancer Center found that the enzyme USP15 could potentially lead to new treatments for breast and pancreatic cancer. Their findings were published in Nature Communications.
Mar 15, 2019
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Scientists at deCODE genetics in Iceland, a subsidiary of Amgen, today publish the first genetic map of the human genome developed using whole-genome sequence data.
Jan 24, 2019
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Studying two rare inherited cancer syndromes, Yale Cancer Center (YCC) scientists have found the cancers are driven by a breakdown in how cells repair their DNA. The discovery, published today in Nature Genetics, suggests ...
Jul 16, 2018
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Genetic recombination between viral strains in bats may have produced the direct evolutionary ancestor of the strain that caused a deadly outbreak of severe acute respiratory syndrome (SARS) in humans, according to new research ...
Nov 30, 2017
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