The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion ...
Jul 9, 2020
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In a Nature paper, CeMM researchers report on the epigenetic and transcriptional regulation in structural cells. They found widespread activity of immune genes, suggesting that structural cells are deeply involved in the ...
Jul 1, 2020
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144
The neighborhood a child grows up in may influence their health for years to come in previously invisible ways.
Jun 19, 2020
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129
Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The ...
Jun 9, 2020
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260
National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of ...
Apr 21, 2020
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242
Biologically important changes in DNA seen in smokers are also being found in people who vape, according to a new study published in the journal Epigenetics.
Feb 12, 2020
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312
Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Due to this mutation, the CFTR protein doesn't embed in cell membranes to form a channel for chlorine ...
Dec 10, 2019
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79
The brain chemical serotonin, a neurotransmitter long known for its role in passing signals between neurons in the brain, can also regulate expression of genes within neurons in an unexpected way, according to research conducted ...
Mar 13, 2019
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519
It takes just 2 percent of the human genome to code for all of the proteins that make cellular functions—from producing energy to repairing tissues—possible.
Feb 26, 2019
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383
When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments.
Feb 8, 2019
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