Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.
Mar 15, 2023
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166
It's a real-life plot worthy of a classic spy novel: Researchers at Massachusetts General Hospital (MGH), the Dana-Farber Cancer Institute and other Boston-area research centers are turning the tables on glioblastomas, the ...
May 11, 2021
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Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment.
Feb 6, 2024
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A regulatory T cell that expresses three specific genes shuts down the mass production of antibodies launched by the immune system to attack invaders, a team led by scientists at The University of Texas MD Anderson Cancer ...
Jul 25, 2011
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Autoimmune diseases such as rheumatoid arthritis and multiple sclerosis happen when the immune system is inadvertently activated, mistakenly attacking the body's tissues and organs. Though it is known that genetics play a ...
Oct 21, 2022
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For the first time, researchers have revealed the different molecular identities of important immune cells, called T regulatory cells, using single cell genomics, in both mouse and human peripheral non-lymphoid tissues such ...
Feb 5, 2019
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Regulatory T cells—work horses of the body's immune system—may also stabilize mood, according to a study. Forkhead box P3 (Foxp3) is a transcription factor that controls the production of regulatory T cells (Tregs).
Aug 23, 2023
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146
An unexpected trick in cancer's playbook may fool an important component of our immune systems into knocking down our natural defenses against solid tumors.
May 13, 2022
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70
A multi-institutional team of researchers has identified an apparently successful treatment for a genetic immune disorder that causes a multitude of health problems - ranging from infections, diabetes, lung disease and the ...
Jul 23, 2015
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A specific group of white blood cells, termed "regulatory T cells," keeps the immune system in balance and suppresses its activity to protect the body against autoimmune diseases. Scientists at the German Center for Neurodegenerative ...
Apr 24, 2019
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