Researchers at The University of Texas MD Anderson Cancer Center have discovered how an aggressive form of prostate cancer called double-negative prostate cancer (DNPC) metastasizes by evading the immune system. The investigators ...
Jul 18, 2019
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The immune system is indispensable for defense against invading pathogens, but its aberrant activation may lead to autoimmune diseases. Regulatory T cells play a crucial role in preventing excess immune activation; mice without ...
Jul 9, 2019
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While therapies that harness the power of the immune system against cancer have made remarkable progress against certain types of tumors, they still remain ineffective in most cancer patients. A new study from the Center ...
May 15, 2019
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An international study led from Karolinska Institutet in Sweden provides new insights into the regulatory T cells' role in protecting against autoimmune disease. By mapping the targets of the immune system in patients with ...
Apr 25, 2019
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A specific group of white blood cells, termed "regulatory T cells," keeps the immune system in balance and suppresses its activity to protect the body against autoimmune diseases. Scientists at the German Center for Neurodegenerative ...
Apr 24, 2019
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New research from the University of Pittsburgh School of Medicine and the UPMC Hillman Cancer Center sheds light on how tumors use the body's regulators of immunity for their own benefit. Published today in Nature Immunology, ...
Apr 1, 2019
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A combination of the experimental histone deacetylase (HDAC) inhibitor entinostat with the anti-PD-1 therapeutic pembrolizumab (Keytruda) showed clinical responses in patients with melanoma that had progressed on prior anti-PD-1 ...
Apr 1, 2019
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Encapsulating human stem-cell-derived beta cells in microcapsules made with a protein that repels key immune cells restored glucose metabolism in diabetic mice and protected the cells from immune system attack, preventing ...
Mar 26, 2019
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Microbes colonize all body surfaces and balance the immune system. In newborn infants, the gut microbiome is first conditioned by breast milk components. When solid food is introduced, gut microbiota develops and bacteria ...
Mar 20, 2019
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Researchers from Universitätsmedizin Berlin have uncovered a critical mechanism that controls immune reactions against microorganisms in the intestine. The results of the international study may contribute to the development ...
Feb 27, 2019
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