Diseases, Conditions, Syndromes

Unique mechanism of action inhibiting paracellular phosphate absorption

Ardelyx, Inc. today announced that the novel mechanism of action for tenapanor for the treatment of hyperphosphatemia, or elevated serum phosphorus, has been published in the peer-reviewed journal Science Translational Medicine. ...

Oncology & Cancer

Use of ibuprofen and similar NSAIDs may shorten life of patients

Ibuprofen, aspirin, and other non-steroidal anti-inflammatory medications are among the most commonly utilized medications in the United States. Primarily for treating pain, inflammation, and preventing cardiovascular disease, ...

Oncology & Cancer

Diagnostic mutations ID'd in chronic kidney disease patients

(HealthDay)—About one-quarter of adults with chronic kidney disease (CKD) of unknown cause or familial nephropathy or hypertension have diagnostic mutations, which can be identified with whole-exome sequencing (WES), according ...

Medical research

Human stem cells used to cure renal anemia in mice

(Medical Xpress)—A team of researchers with Kyoto University and Kagawa University, both in Japan, has cured renal anemia in mice by injecting them with treated human stem cells. In their paper published in Science Translational ...

Sleep disorders

CPAP doesn't alter renal function in coexisting OSA, CVD

(HealthDay)—For individuals with coexisting obstructive sleep apnea (OSA) and cardiovascular disease, continuous positive airway pressure (CPAP) does not alter renal function, according to a study published online July ...

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