Diseases, Conditions, Syndromes

Sex differences in kidney gene expression

Male and female rats show different patterns of kidney gene expression throughout their lives, a study in the open access journal Biology of Sex Differences reveals. The finding could help explain some of the gender differences ...

Diseases, Conditions, Syndromes

Identification of a driver of fibrosis in chronic kidney disease

Chronic kidney disease can develop in response to a variety of insults and is characterized by progressive renal fibrosis and atrophy of kidney tubule. Therapeutic options are limited and the disease is often not detected ...

Diseases, Conditions, Syndromes

Chronic kidney disease alters intestinal microbial flora, study finds

(Medical Xpress)—Chronic kidney disease changes the composition of intestinal bacterial microbes that normally play a crucial role in staving off disease-causing pathogens and maintaining micronutrient balance, according ...

Diseases, Conditions, Syndromes

Higher risk of VTE in CKD surgical patients on enoxaparin

(HealthDay) -- For patients with chronic kidney disease (CKD) who undergo total hip replacement (THR), the rate of major venous thromboembolism (VTE) is significantly higher in those treated with enoxaparin compared to those ...

Diseases, Conditions, Syndromes

Unique mechanism of action inhibiting paracellular phosphate absorption

Ardelyx, Inc. today announced that the novel mechanism of action for tenapanor for the treatment of hyperphosphatemia, or elevated serum phosphorus, has been published in the peer-reviewed journal Science Translational Medicine. ...

Diseases, Conditions, Syndromes

Serious acute kidney injury: More common than ever

Acute kidney injury (AKI), an abrupt or rapid decline in kidney function, is a serious and increasingly prevalent condition that can occur after major infections, major surgery, or exposure to certain medications. The incidence ...

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