Health
Study reveals tobacco's toll on women's placentas
Smoking while pregnant causes severe DNA damage to cells in the placenta and significantly impairs its function, new University of Otago research suggests.
Dec 4, 2013
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Page 4 - News tagged with repair mechanism
Genetics
Gene controls three different diseases
An international research consortium led by the Universitat Autònoma de Barcelona (UAB), the CIBERER and the University of Wurzburg (Germany) has discovered a gene that can cause three totally different diseases, depending ...
Apr 25, 2013
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Cardiology
Gene therapy may activate stem cells in heart failure patients
(HealthDay)—Delivery of an SDF-1 encoding plasmid (JVS-100) acts a homing signal for stem cells and improves clinical status in patients with symptomatic heart failure due to ischemic cardiomyopathy (IsCM), according to ...
Feb 22, 2013
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Oncology & Cancer
Cancer biology: Keeping bad company
The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of tumorigenesis. ...
Jan 16, 2013
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Oncology & Cancer
Researchers uncover novel role of BRCA1 in regulating the survival of skin stem cells
Our DNA, which stores our genetic information, is constantly exposed to damage. If not properly repaired, DNA damage can lead to cell death. This, in turn, can lead to tissue exhaustion and ageing, or induce mutations resulting ...
Jan 3, 2013
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Neuroscience
Engineered flies spill secret of seizures
In a newly reported set of experiments that show the value of a particularly precise but difficult genetic engineering technique, researchers at Brown University and the University of California–Irvine have created a Drosophila ...
Oct 11, 2012
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Oncology & Cancer
Genomic study shows colon and rectal tumors constitute a single type of cancer
The pattern of genomic alterations in colon and rectal tissues is the same regardless of anatomic location or origin within the colon or the rectum, leading researchers to conclude that these two cancer types can be grouped ...
Jul 18, 2012
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Genetics
Zebrafish reveal promising mechanism for healing spinal cord injury
Scientists in Australia are studying the mechanisms of spinal cord repair in zebrafish, which unlike humans and other mammals can regenerate their spinal cord following injury. Their findings suggest a family of molecules ...
Jul 6, 2012
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Medical research
Exercise triggers stem cells in muscle
University of Illinois researchers determined that an adult stem cell present in muscle is responsive to exercise, a discovery that may provide a link between exercise and muscle health. The findings could lead to new therapeutic ...
Feb 6, 2012
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Medical research
Oxidative DNA damage repair
Oxidative stress damages DNA. Researchers in the Vetsuisse Faculty have now decoded the mechanism that repairs DNA damaged in this way. This repair mechanism could lead to less invasive approaches in cancer therapy and contribute ...
Dec 27, 2011
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