A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes. The findings, ...
Jul 20, 2016
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Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell—sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet over the course of a ...
Apr 12, 2016
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Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. They also found that manipulating these signals can enhance ...
Apr 11, 2016
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A new study from The Ottawa Hospital and the University of Ottawa is poised to completely change our understanding of Duchenne muscular dystrophy and pave the way for far more effective treatments.
Nov 16, 2015
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DNA double-strand breaks (DSBs) are the worst possible form of genetic malfunction that can cause cancer and resistance to therapy. New information published this week reveals more about why this occurs and how these breaks ...
Aug 3, 2015
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Ah, summer. People are outside enjoying the warm weather, swimming, playing, or just soaking up that glorious, skin-damaging, high-energy UV radiation from the sun.
Jun 5, 2014
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Scientists led by a group of researchers at The Scripps Research Institute (TSRI) in La Jolla, CA, have discovered some of the key proteins involved in one type of DNA repair gone awry.
May 22, 2014
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Throughout a cell's life, corrective mechanisms act to repair DNA strand breaks. The exception is during the critical moment of cell division, when chromosomes are most vulnerable. Toronto researchers found out why DNA repair ...
Mar 20, 2014
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Scientists at the University of Bristol have discovered that a mechanism for preventing mutation within important genes involves long distance scanning of DNA by a molecular motor protein.
Feb 19, 2014
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By detailing a process required for repairing DNA breakage, scientists at the Duke Cancer Institute have gained a better understanding of how cells deal with the barrage of damage that can contribute to cancer and other diseases.
Sep 30, 2013
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