Neuroscience

How aging can intensify damage of spinal cord injury

In the complex environment of a spinal cord injury, researchers have found that immune cells in the central nervous system of elderly mice fail to activate an important signaling pathway, dramatically lowering chances for ...

Diseases, Conditions, Syndromes

Genetic mutation causes lupus in mice

Yale researchers have identified a genetic mutation that leads to lupus in mice. The discovery could open the way for development of therapies that target the mutation. The study appears in Cell Reports.

Oncology & Cancer

A circuitous route to therapy resistance

Gliomas are malignant brain tumors that arise from glial cells called astrocytes, found in the central nervous system. "In treating malignant gliomas, we currently combine radiotherapy with the anticancer drug temozolomide. ...

Oncology & Cancer

Ovarian cancer patients survive longer with BRCA2 mutated in tumors

Women with high-grade ovarian cancer live longer and respond better to platinum-based chemotherapy when their tumors have BRCA2 genetic mutations, researchers at The University of Texas MD Anderson Cancer Center and the Institute ...

page 4 from 5