Cancer's resistance to chemotherapy could be reversed by targeting lactate—the product that builds up as cancer cells convert nutrients to energy, according to new research published in Nature.
Jul 4, 2024
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Bowel cancer cells have the ability to regulate their growth using a genetic on-off switch to maximize their chances of survival, a phenomenon that's been observed for the first time by researchers at UCL and University Medical ...
Jul 3, 2024
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A group has proposed a new concept of mechanobiomaterials, which is inspired by the natural phenomenon that biomechanics mediate tissue repair and regeneration. The rationale behind this new concept is to program the biological ...
Jun 28, 2024
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Researchers at the Pacific Northwest Research Institute (PNRI) and collaborating institutions have made a discovery that could significantly advance our understanding of genomic disorders. Their latest study, published in ...
Jun 21, 2024
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Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists from the German Cancer Research Center (DKFZ) and the Universities of Cambridge and Edinburgh have analyzed ...
Jun 13, 2024
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A new research paper titled "Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy" has been published in Oncotarget.
Jun 5, 2024
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TREX1 is a gene that is supposed to direct the maintenance of the entire body's DNA, but new research shows that when people are born with mutated TREX1, it causes catastrophic damage to the DNA over time, resulting in a ...
Jun 4, 2024
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A recent study shows that there may be a more effective way to treat melanoma by using ascorbate (vitamin C) to increase DNA damage in cancer cells, leading to their death, according to co-corresponding author of the study ...
Jun 3, 2024
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Researchers have discovered a more efficient method for evaluating the ability of mesenchymal stromal cells (MSCs) to regenerate cartilage. Their novel method is also the first to utilize topological defects in the self-assembly ...
May 28, 2024
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In an editorial, in Oncoscience titled "Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy," researcher Ioannis A. Voutsadakis from Sault Area Hospital and Northern Ontario School of Medicine ...
May 13, 2024
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