A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes. The findings, ...
Jul 20, 2016
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Combination antiretroviral therapy (cART) suppresses HIV replication and significantly slows the progression of disease, enabling HIV+ individuals to effectively manage infection for long periods. One of the manifestations ...
Jul 7, 2016
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Scientists from the Institute for Basic Science (IBS) have successfully inhibited the growth of colon tumors in mice with mismatch repair deficiency. The research team, headed by the Center's director MYUNG Kyungjae, made ...
Jun 15, 2016
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Contextual factors, such as the race of participants in an experiment or the geography of where the experiment was run, can reduce the likelihood of replicating psychological studies, a team of New York University researchers ...
May 23, 2016
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A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress ...
May 18, 2016
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Although combinatorial antiretroviral therapies (cARTs) have dramatically reduced the occurrence of HIV-1-related dementia and encephalitis, recent studies have shown a rise in the number of HIV-positive individuals who will ...
May 9, 2016
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How long you live depends in part on the genes you inherit. For example, those suffering from Werner's syndrome have inherited two defective copies of a gene coding for an enzyme that is involved in DNA replication and repair.
May 2, 2016
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When it comes to replicating their DNA so they can propagate, normal cells are perfectionists. Cancer cells, on the other hand, have no problem tolerating mistakes while copying their DNA. In fact, messed-up DNA is a big ...
Apr 28, 2016
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80
A new Yale-led study suggests that death from influenza virus in older people may be primarily caused by a damaging immune response to flu and not by the virus itself. The insight could lead to novel strategies for combating ...
Apr 21, 2016
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Investigators in the Division of Infectious Diseases at the University of North Carolina School of Medicine have clearly demonstrated that HIV infects and reproduces in macrophages, large white blood cells found in the liver, ...
Mar 8, 2016
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