During infection, HIV places copies of its genome into the DNA of cells, creating what is known as a viral reservoir. In this state, the virus effectively hides from anti-HIV drugs and the body's immune response. In most ...
Nov 15, 2021
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With the successful suppression of the AIDS virus (HIV) through medication, the focus turns toward its eradication. Researchers from Kumamoto University in Japan have developed a new compound that is key to the destruction ...
Oct 2, 2017
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For the first time in humans, a research team has shown that, as early as the first days of infection, HIV is able to create reservoirs where it will hide and persist during antiretroviral therapy.
Feb 28, 2023
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A team of international scientists led by Northwestern University found that HIV is still replicating in lymphoid tissue, even when it is undetectable in the blood of patients on antiretroviral drugs.
Jan 27, 2016
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Scientists have long known that even in the face of antiretroviral therapy, some HIV virus remains in infected individuals forever, hiding in small reservoirs of cells of the immune system. When these individuals discontinue ...
Apr 30, 2020
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Antiretroviral therapy (ART) can suppress HIV to the point where the virus is nearly undetectable, and people on medication can live many years. But therapy cannot completely eradicate the virus; it persists in reservoirs ...
Oct 9, 2019
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Researchers associated with the AIDS Clinical Trials Group (ACTG) have published a study titled "Varied Patterns of Decay of Intact HIV-1 Proviruses over Two Decades of ART" in the Journal of Infectious Diseases.
Mar 27, 2023
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With more than 35 million people worldwide living with the virus and nearly 2 million new cases each year, the human immunodeficiency virus (HIV) remains a major global epidemic. Existing antiretroviral drugs do not cure ...
Oct 3, 2018
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HIV hides in reservoirs during antiretroviral therapy (ART). These viral sanctuaries are the reason why ART is not a cure. And research teams have striven for years to determine how the HIV reservoirs are established and ...
Mar 4, 2020
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Soon after infection, HIV-1 establishes a life-long presence by forming viral reservoirs in the body—cells that are infected with HIV but not actively producing new viruses. Antiretroviral therapy (ART) reduces HIV levels ...
Jan 10, 2023
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