A recent study that shows manipulating and deleting a specific gene (AMN1) from yeast could provide a foundation for a new approach to combatting drug resistance when treating microbial infections or cancer. Led by Gábor ...
Apr 15, 2022
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While gene mutations can lead to drug resistance, researchers in the Perelman School of Medicine at the University of Pennsylvania have identified an important, non-genetic adaptation that could also drive resistance to targeted ...
Mar 1, 2022
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Drug resistance is a major obstacle in the treatment of cancers. In an aggressive type of pancreatic cancer, for instance, drug resistance is associated with the suppression of programmed cell death, which results in the ...
Feb 24, 2022
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Precision therapies targeting melanoma and other cancers have improved patient survival, but tumors often stop responding to drugs, and recent studies point to changes in DNA—both inside and outside chromosomes—as a driving ...
Dec 20, 2021
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Scientists have tracked and analyzed cancer cell behavior with a novel cellular "barcoding technology."
Dec 9, 2021
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New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors. The ...
Nov 24, 2021
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Obesity, insulin resistance and Type 2 diabetes are risk factors for breast cancer in post-menopausal women. The metabolic and inflammatory complications of obesity have a role in the formation of cancer. However, the cellular ...
Nov 23, 2021
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Glasgow scientists have uncovered important information about how cancer cells become resistant to certain treatments, according to research published in Nature Communications.
Nov 17, 2021
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82
A new industry-academic partnership between the University of Oxford and biopharmaceutical company NuCana as found that chemotherapy drug NUC-7738, derived from a Himalayan fungus, has 40 times greater potency for killing ...
Oct 11, 2021
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The Nobel season opens on Monday with the pioneers of mRNA Covid-19 vaccines and immune system research tipped for the medicine prize, which kicks off a week of awards against the backdrop of the pandemic.
Oct 4, 2021
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