A longstanding question has nagged the COVID battle for more than four years: Why does the infection cause severe disease in older people? The question has remained despite a global cadre of medical investigators having produced ...
Researchers have for the first time created an integrated single-cell RNA sequencing (scRNAseq) atlas of the human periodontium, the specialized tissues in the mouth that connect teeth to the underlying bone. This atlas will ...
Jun 14, 2024
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The largest genetic analysis of an autoimmune disorder known as systemic sclerosis ever conducted in an Asian population has uncovered six new DNA markers for this rare tissue disease—a discovery that promises to improve ...
Jun 13, 2024
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A new study from Yale School of Medicine has shown that the neurons that generate higher cognition, and are a target of pathology in Alzheimer's disease and mental disorders such as schizophrenia, express an enrichment of ...
Jun 13, 2024
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While most cell types experience a functional decline after years of proliferation and replication, T cells can proliferate seemingly indefinitely and without detriment.
Jun 12, 2024
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Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.
Jun 12, 2024
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Northwestern Medicine scientists have discovered that an attenuated (weakened) virus can help eliminate cancer in mice. In addition, mice that were treated with this virus were more resistant to developing tumors later in ...
Jun 11, 2024
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Checkpoint immunotherapy utilizing PD-1 blockade has become the standard of care for metastatic melanoma. While this treatment is effective in 40% of patients, the other 60% develop resistance, leading to tumor regrowth. ...
Jun 10, 2024
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When scientists transplanted the gut microbes of aged mice into young "germ-free" mice—raised to have no gut microbes of their own—the recipient mice experienced an increase in inflammation that parallels inflammatory ...
Jun 10, 2024
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Researchers have just taken the most fine-grained look to date at inflammatory pain: increased sensitivity to pain that follows an immune response to a wound, infection, sunburn, arthritis, or other trigger.
Jun 5, 2024
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