A new article published in the Cell Reports describes how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett syndrome in preclinical models. The study was led by Dr. Manel Esteller, ...
May 15, 2018
0
3
It is a parent's nightmare: a child is born apparently healthy, then stops meeting developmental milestones at one year old. Her verbal and motor skills vanish, and irregular breathing, seizures, and a host of other problems ...
Jan 29, 2018
0
150
A study from a team of Massachusetts General Hospital (MGH) investigators points toward a potential strategy for treating X-linked disorders - those caused by mutations in the X chromosome - in females. Their report published ...
Jan 4, 2018
0
44
Vanderbilt University researchers have relieved symptoms of Rett syndrome in a mouse model with a small molecule that works like the dimmer switch in an electrical circuit.
Aug 23, 2017
0
65
New research into Rett syndrome therapeutics suggests that a small molecule already reported to improve respiratory problems associated with the disease may also improve spatial memory and motor skill defects.
Jul 5, 2017
0
3
A translational, multicenter study has unveiled the potential of D-serine—a dietary supplement—to improve the neuronal function of a patient with a mutation of the glutamate receptors associated to atypical Rett syndrome ...
Jul 4, 2017
0
29
Fresh discoveries about a range of neurological disorders may inform the development of new therapies.
Mar 27, 2017
0
29
Researchers have uncovered 30 genes that could, one day, serve as therapeutic targets to reverse Rett syndrome, a rare neurological disorder that affects only girls and is a severe form of an autism spectrum disorder.
Jan 30, 2017
0
88
Neurodevelopmental disorders like autism very likely have their origin at the dawn of life, with the emergence of inappropriate connectivity between nerve cells in the brain. In one such disorder, Rett syndrome, the pathology ...
Jan 18, 2017
0
211
Researchers at the University of Alabama at Birmingham are part of the international STARS study to see if a drug originally developed for Parkinson's disease might help reduce breathing issues common in patients with Rett ...
Dec 19, 2016
0
364
