Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA—a crucial regulatory step before proteins are created. Then, organs develop and hopefully ...
Apr 27, 2022
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Recent work from the laboratory of Elena Martinelli, Ph.D., MPH, professor of Medicine in the Division of Infectious Diseases and of Microbiology–Immunology, has discovered how inhibiting an immune cell singling pathway ...
Mar 7, 2024
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Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens. Bacterial defenses, such as CRISPR-Cas systems, have diverse proteins ...
Jan 4, 2023
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In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis. A recent addition to the toolkit, RNA sequencing, has been demonstrated to help researchers narrow down disease ...
Oct 27, 2020
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A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver ...
Apr 13, 2023
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Calcium channel blockers may improve treatment for pancreatic cancer patients receiving gemcitabine-based chemotherapy, according to recent findings published in the Proceedings of the National Academy of Sciences.
Jun 22, 2022
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Neurons, the main cells that make up our brain and spinal cord, are among the slowest cells to regenerate after an injury, and many neurons fail to regenerate entirely. While scientists have made progress in understanding ...
Oct 16, 2023
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Surgical teams at NYU Langone Health performed the world's first genetically modified pig kidney transplant into a human body in September and November 2021, and then transplanted two pig hearts in the summer of 2022. These ...
May 21, 2024
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Researchers at the University of Tsukuba have revealed two molecules in the brain of a sea squirt that specify the development of a hypothalamus-like region, also shedding light on how different parts of the brain form in ...
Sep 20, 2018
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Sequencing RNA, not just DNA, could help doctors predict how prostate cancer tumors will respond to treatment, according to research published in the open access journal Genome Biology. Because a tumor's RNA shows the real ...
Aug 25, 2014
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