A 3-D bioengineered model of lung tissue built by University of Michigan researchers is poking holes in decades worth of flat, Petri dish observations into how the deadly disease pulmonary fibrosis progresses.
Sep 14, 2020
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New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack. The study, published in the journal Cell, reveals that a protein known as type 5 collagen ...
Jul 6, 2020
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Billions of cardiac muscle cells are lost during a heart attack. The human heart cannot replenish these lost cells, so the default mechanism of repair is to form a cardiac scar. While this scar works well initially to avoid ...
Jan 30, 2020
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Heart disease remains the largest killer in Australia and around the world. A new study has shown that a protein therapy- recombinant human platelet-derived growth factor-AB (rhPDGF-AB) - could improve outcomes following ...
Jan 2, 2020
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Abnormal scarring is a serious threat resulting in non-healing chronic wounds or fibrosis. Scars form when fibroblasts, a type of cell of connective tissue, reach wounded skin and deposit plugs of extracellular matrix. Until ...
Nov 27, 2019
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The buildup of scar tissue makes recovery from torn rotator cuffs, jumper's knee, and other tendon injuries a painful, challenging process, often leading to secondary tendon ruptures. New research led by Carnegie's Chen-Ming ...
Nov 25, 2019
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The fight against liver disease could be helped by the discovery of cells that cause liver scarring.
Oct 9, 2019
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Idiopathic pulmonary fibrosis (IPF) is a type of lung disease that results in scarring of the lungs, also known as fibrosis. Over time, the fibrosis gets increasingly worse so that it becomes hard for those with the condition ...
Sep 25, 2019
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Cuts, scrapes, blisters, burns, splinters, and punctures—there are a number of ways our skin can be broken. Most treatments for skin wounds involve simply placing a barrier over it (usually an adhesive gauze bandage) to ...
Jul 24, 2019
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Every year 790,000 Americans suffer a heart attack, which leaves damaged scar tissue on the heart and limits its ability to beat efficiently. But what if scientists could reprogram scar tissue cells called fibroblasts into ...
Jun 20, 2019
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