Enlarged cerebral ventricles are found in 80% of individuals with schizophrenia, yet the mechanisms that lead to ventricular enlargement are mostly unknown. Scientists at St. Jude Children's Research Hospital have found that ...
Feb 14, 2020
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Excessive activity of an immune system gene previously linked to schizophrenia reproduces neural and behavioral aspects of the disease in mice, according to a new study publishing on January 14 in the open-access journal ...
Jan 14, 2020
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Researchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding ...
Oct 24, 2019
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Researchers have discovered that gene expression regulators work together to raise an individual's risk of developing schizophrenia. Schizophrenia-like gene expression changes modeled in human neurons matched changes found ...
Sep 23, 2019
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Using computational tools to investigate gene transcription networks in large collections of brain tissues, a scientific team has identified a gene that acts as a master regulator of schizophrenia during early human brain ...
Sep 11, 2019
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Using a unique computational framework they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute (VGI) has identified ...
Apr 19, 2019
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In the largest study of its kind, involving more than 100,000 people, researchers at the Icahn School of Medicine at Mount Sinai have applied a novel machine learning method to identify 413 genetic associations with schizophrenia ...
Mar 25, 2019
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Genetic variants which prevent a neurotransmitter receptor from working properly have been implicated in the development of schizophrenia, according to research by the UCL Genetics Institute.
Jan 18, 2019
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A large-scale genetic study found that some of the same genes associated with the use of cannabis are also associated with certain personality types and psychiatric conditions. The study, published in Nature Neuroscience, ...
Aug 28, 2018
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Hiding in plain sight, new research shines a spotlight on the placenta's critical role in the nature versus nurture debate and how it confers risk for schizophrenia and likely other neurodevelopmental disorders including ...
May 28, 2018
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