Medical research

New target explored for psychiatric drug development

(Medical Xpress)—In a surprising discovery, neuroscientists have found that a breakdown product of cholesterol in the brain may be a target for developing new drugs to treat schizophrenia and other mental illnesses.

Neuroscience

Brain wiring quiets the voice inside your head

During a normal conversation, your brain is constantly adjusting the volume to soften the sound of your own voice and boost the voices of others in the room.

Neuroscience

Scientists find key signal that guides brain development

Scientists at The Scripps Research Institute (TSRI) have decoded an important molecular signal that guides the development of a key region of the brain known as the neocortex. The largest and most recently evolved region ...

Neuroscience

Distinct brain disorders biologically linked

A team of researchers have shown that schizophrenia and a disorder associated with autism and learning difficulties share a common biological pathway. This is one of the first times that researchers have uncovered genetic ...

Genetics

Stray prenatal gene network suspected in schizophrenia

Researchers have reverse-engineered the outlines of a disrupted prenatal gene network in schizophrenia, by tracing spontaneous mutations to where and when they likely cause damage in the brain. Some people with the brain ...

Diseases, Conditions, Syndromes

Lead acts to trigger schizophrenia

Mice engineered with a human gene for schizophrenia and exposed to lead during early life exhibited behaviors and structural changes in their brains consistent with schizophrenia. Scientists at Columbia University's Mailman ...

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