Psychology & Psychiatry

Why some antidepressants may initially worsen symptoms

New research helps explain a paradoxical effect of certain antidepressants—that they may actually worsen symptoms before helping patients feel better. The findings, highlighted in a paper publishing online December 17 in ...

Psychology & Psychiatry

Ketamine cousin rapidly lifts depression without side effects

GLYX-13, a molecular cousin to ketamine, induces similar antidepressant results without the street drug side effects, reported a study funded by the National Institute of Mental Health (NIMH) that was published last month ...

Neuroscience

How a popular antidepressant drug could rewire the brain

Prozac, the trade name for the drug fluoxetine, was introduced to the U.S. market for the treatment of depression in 1988. Thirty years later, scientists still don't know exactly how the medication exerts its mood-lifting ...

Psychology & Psychiatry

Antidepressants may reduce anxiety more than depressive symptoms

One of the most common antidepressants, sertraline, leads to an early reduction in anxiety symptoms, commonly found in depression, several weeks before any improvement in depressive symptoms, a UCL-led clinical trial has ...

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