Senescent cells, which stop dividing under stress, are long- recognized drivers of multiple diseases of aging. Mouse studies have shown that targeted removal of these cells and the inflammatory factors they secrete, known ...
Jan 16, 2020
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In human, the skin is one of the organs that exhibit early-onset aging-associated dysfunction. As a critical physical barrier, the skin is composed of a variety of cell types including fibroblasts and keratinocytes. Due to ...
Nov 27, 2020
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Researchers from Kumamoto University in Japan have used comprehensive genetic analysis to find that the enzyme NSD2, which is known to regulate the actions of many genes, also works to block cell aging. Their experiments ...
Aug 7, 2020
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A Mayo Clinic study has shown evidence linking the biology of aging with idiopathic pulmonary fibrosis, a disease that impairs lung function and causes shortness of breath, fatigue, declining quality of life, and, ultimately, ...
Feb 23, 2017
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Researchers at Mayo Clinic have shown that eliminating cells that accumulate with age could prevent or delay the onset of age-related disorders and disabilities. The study, performed in mouse models, provides the first evidence ...
Nov 2, 2011
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In a study recently published in Nature, University of Minnesota Medical School researchers found that senescent immune cells are the most dangerous type of senescent cell.
May 12, 2021
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Zombie cells are the ones that can't die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, ...
Sep 19, 2018
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A particular type of white blood cell becomes more pro-inflammatory as it deteriorates with age or 'senesce', according to research led by A*STAR scientists.
Oct 4, 2018
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A study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alzheimer's disease can reduce brain damage and inflammation, and slow the pace of cognitive decline. ...
May 1, 2019
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Valproic acid—a drug used to treat epilepsy, migraine, and bipolar disorder—can cause birth defects when taken during pregnancy. Now, a study publishing June 14 in the open access journal PLOS Biology by Bill Keyes of ...
Jun 14, 2022
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