Senescence is a response to cell damage and stress characterized by the arrest of the cell cycle. When aging, cells permanently stop dividing, thus preventing the propagation of damaged and dysfunctional cells. However, eventually, ...
May 5, 2020
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A study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of stem-like chemoresistant cells following cisplatin treatment. Researchers showed that a combination ...
Dec 20, 2019
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Ageing is a dramatic public health issue in the face of the current demographic changes: the proportion of 60 and over in the world's population will almost double by 2050. In this context, a new discovery has just broadened ...
Dec 9, 2019
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Since the time of the ancient Greeks, doctors and philosophers have argued whether ageing is a disease or a natural process. Many authors of the Hippocratic Corpus argued that growing old invariably leads to frailty, disability ...
Nov 27, 2019
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Given the opportunity to live much longer lives, many of us might feel less than thrilled at the prospect. After all, you might think, who would want to live an extra 20 years dealing with arthritis, dementia or heart problems?
Oct 28, 2019
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A classic boxing move, the "one-two punch," could also be effective against cancer: a left jab knocks cancer cells senseless, quickly followed by a right hook that knocks them out altogether. Researchers at the Netherlands ...
Oct 3, 2019
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In a small safety and feasibility clinical trial, Mayo Clinic researchers have demonstrated for the first time that senescent cells can be removed from the body using drugs termed "senolytics". The result was verified not ...
Sep 18, 2019
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Researchers from the Tulane University School of Medicine have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. The study, which will be published September 17 in the Journal ...
Sep 17, 2019
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New research from the USC Viterbi School of Engineering could be key to our understanding of how the aging process works. The findings potentially pave the way for better cancer treatments and revolutionary new drugs that ...
Jul 25, 2019
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Some of the damaging cell effects linked to ageing could be prevented by manipulating tiny parts of cells, a study shows.
Feb 14, 2019
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