Medical research

Researchers uncover new agents

Mayo Clinic researchers have uncovered three new agents to add to the emerging repertoire of drugs that aim to delay the onset of aging by targeting senescent cells - cells that contribute to frailty and other age-related ...

Medical research

Cellular senescence prevented by the SETD8 enzyme

An enzyme that blocks cellular senescence and its mechanisms has been discovered by a research team from Kumamoto University, Japan. They found that a reduction of the enzyme SETD8, which regulates cell proliferation and ...

Oncology & Cancer

Fir extract could have anti-cancer and anti-aging properties

Scientists from the Engelhardt Institute of Molecular Biology and MIPT have studied the effects of Siberian fir terpenoids on senescent and human cancer cell lines at the genetic level. Research into terpenoids, including ...

Oncology & Cancer

Senescence promotes chemotherapy side effects and cancer relapse

Standard chemotherapy is a blunt force instrument against cancer – and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both malignant and healthy, ...

Medical research

Anti-aging therapies targeting senescent cells: Facts and fiction

It's an exciting time to be an elderly mouse. Researchers believe that by removing senescent cells (cells with a persistent damage response), which naturally accumulate with age, senior rodents can regrow hair, run faster, ...

Genetics

Genes that control cellular senescence identified

A research group including Professor KAMADA Shinji, Research Fellow NAGANO Taiki (both from the Kobe University Biosignal Research Center), and Unit Chief ENARI Masato (National Cancer Research Institute) has succeeded in ...

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