Oncology & Cancer

Researchers identify key factors impacting adaptive cancer therapy

Most cancer treatments are based on using the maximum tolerated dose of a drug to kill as many cancer cells as possible. While this approach has led to patients achieving good responses to therapy, most patients develop drug ...

Neuroscience

'The focea': A region of improved vision in mice

Mice are an important animal model of human vision due to the powerful genetic tools available in this species. However, mouse vision was thought to be different to that of humans because humans have a region of the retina ...

Neuroscience

DNA damage 'hot spots' discovered within neurons

Researchers at the National Institutes of Health (NIH) have discovered specific regions within the DNA of neurons that accumulate a certain type of damage (called single-strand breaks or SSBs). This accumulation of SSBs appears ...

Medical research

Scientists create functional human retinas in a dish

Scientists have generated accurate replications of human retinas in culture that can be used to pinpoint the specific types of cells affected by genetic eye diseases. The culmination of a six-year effort, this achievement ...

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