Medical research

Scientists create functional human retinas in a dish

Scientists have generated accurate replications of human retinas in culture that can be used to pinpoint the specific types of cells affected by genetic eye diseases. The culmination of a six-year effort, this achievement ...

Medical research

Study finds important factor in fat storage and energy metabolism

As part of their ongoing research on the physiologic factors that contribute to the development of obesity, Joslin Diabetes Center scientists have identified a cell cycle transcriptional co-regulator – TRIP-Br2 – that ...

Neuroscience

Newly developed chemical restores light perception to blind mice

Progressive degeneration of photoreceptors—the rods and cones of the eyes—causes blinding diseases such as retinitis pigmentosa and age-related macular degeneration. While there are currently no available treatments to ...

Oncology & Cancer

First volume of the Cancer Cell Line Encyclopedia made public

The goal of cancer treatment is to match the right drug to the right target in the right patient. But before such "personalized" drugs can be developed, more knowledge is needed about specific genomic alterations in cancers ...

Medical research

Blocking obesity-associated protein stops dangerous fat formation

Visceral fat deposits around internal organs in the stomach are particularly harmful: they are associated with insulin resistance, type-2 diabetes and heart disease. The study, conducted in close collaboration with researchers ...

Parkinson's & Movement disorders

Study reveals promising new target for Parkinson's disease therapies

With a new insight into a model of Parkinson's disease, researchers from the University of Pennsylvania School of Veterinary Medicine have identified a novel target for mitigating some of the disease's toll on the brain.

Oncology & Cancer

The path to personalized cancer treatment

In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. The study is published in Nature on Thursday 29 ...

Diabetes

Exercise induces hypothalamic cell proliferation in mice

(HealthDay)—Exercise training induces hypothalamic cell proliferation in adult mice and improves insulin sensitivity, but blocking cell proliferation does not prevent insulin action, according to an experimental study published ...

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