Oncology & Cancer

Current cancer drug discovery method flawed, study finds

The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers report May 2 in Nature Methods. The findings cast doubt on methods used by the entire scientific enterprise ...

Medical research

Resveratrol falls short in health benefits

Resveratrol, an ingredient in red wine thought to improve insulin sensitivity, reduce risk of heart disease and increase longevity, does not appear to offer these benefits in healthy women, new research at Washington University ...

Medical research

Key link between obesity and type 2 diabetes discovered

(Medical Xpress)—New research published in the journal Cell Metabolism has identified a key mechanism in the immune system involved in the development of obesity-linked type 2 diabetes. The findings open up new possibilities ...

Oncology & Cancer

Researchers identify key factors impacting adaptive cancer therapy

Most cancer treatments are based on using the maximum tolerated dose of a drug to kill as many cancer cells as possible. While this approach has led to patients achieving good responses to therapy, most patients develop drug ...

Medical research

A boost in microRNA may protect against obesity and diabetes

Obesity, which is associated with low-grade inflammation, is an important contributor in the development of diabetes and cardiovascular disease. While the role of several organs including adipose tissue have been implicated ...

Neuroscience

Optogenetics has 'completely changed neuroscience'

It's getting harder to find the line between science and science fiction. One of the hot research techniques these days, "optogenetics," uses gene therapy to deliver light-sensitive proteins to specific cells. Then researchers ...

Neuroscience

DNA damage 'hot spots' discovered within neurons

Researchers at the National Institutes of Health (NIH) have discovered specific regions within the DNA of neurons that accumulate a certain type of damage (called single-strand breaks or SSBs). This accumulation of SSBs appears ...

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