Neuroscience

Common protein in skin can 'turn on' allergic itch

A commonly expressed protein in skin—periostin—can directly activate itch-associated neurons in the skin, according to new research from North Carolina State University. The researchers found that blocking periostin receptors ...

Medications

Pain relief at a lower opioid dose

A team of researchers at Johns Hopkins have found that activating nerve cell receptors along two chemical pathways—one that has previously been linked to how the brain senses "itch"—may improve pain relief when combined ...

Medical research

Research explains link between exercise and appetite loss

Ever wonder why intense exercise temporarily curbs your appetite? In research described in today's issue of PLOS Biology, Albert Einstein College of Medicine researchers reveal that the answer is all in your head—more specifically, ...

Neuroscience

Long-sought 'warm-sensitive' brain cells identified in new study

A new UC San Francisco study challenges the most influential textbook explanation of how the mammalian brain detects when the body is becoming too warm, and how it then orchestrates the myriad responses that animals, including ...

Neuroscience

Fish courtship pheromone uses the brain's smell pathway

Research at the RIKEN Brain Science Institute in Japan has revealed that a molecule involved in fish reproduction activates the brain via the nose. The pheromone is released by female zebrafish and sensed by smell receptors ...

Neuroscience

Deciphering the olfactory receptor code

In animals, numerous behaviors are governed by the olfactory perception of their surrounding world. Whether originating in the nose of a mammal or the antennas of an insect, perception results from the combined activation ...

Medical research

Blocking pain receptors found to extend lifespan in mammals

Blocking a pain receptor in mice not only extends their lifespan, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood sugar.

Neuroscience

Researchers find new target for chronic pain treatment

Researchers at the UNC School of Medicine have found a new target for treating chronic pain: an enzyme called PIP5K1C. In a paper published today in the journal Neuron, a team of researchers led by Mark Zylka, PhD, Associate ...

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