Smoking-related DNA methylation patterns explain around a fifth of the variation in body mass index (BMI) between individuals, according to a study publishing September 9th in the open-access journal PLOS Genetics, led by ...
Sep 9, 2021
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Scientists at UCL and the Francis Crick Institute, London, have developed a new tool, which can rapidly estimate the number of T cells (immune cells) in a cancerous tumor; with T cell abundance helping predict a patient's ...
Sep 8, 2021
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Post-traumatic osteoarthritis—caused by degraded cartilage that cushions the ends of bones in joints—occurs after a joint injury. With the knowledge that PTOA will lead to earlier onset and faster progression of osteoarthritis ...
Sep 1, 2021
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COVID-19 took its largest toll on residents of U.S. nursing homes. Prior to the vaccine roll-out, many states reported that over a third of all cases and deaths occurred amongst this vulnerable population.
Aug 27, 2021
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Fast isolation of infected individuals is key to containing any outbreak of COVID-19, including the Delta variant, and contact tracing is a critical part of this process.
Aug 18, 2021
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If you've ever seen a petunia with artfully variegated petals, then you've seen transposons at work. The flower's showy color patterns are due to transposable elements, or DNA sequences that can move locations within a genome. ...
Aug 17, 2021
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The pandemic has enabled us to study the details of how evolution happens—in real time. Scientists have generated more than two million genome sequences of the SARS-CoV-2 virus, allowing us to dissect the minutiae of evolutionary ...
Aug 12, 2021
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The challenges posed by the COVID-19 pandemic have stimulated innovation on several fronts. One is the development of low-cost methods of clinical diagnosis. Genosensors are a case in point. Based on nucleic acids that detect ...
Aug 10, 2021
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A one-time analysis of entire-tumor DNA is almost always sufficient to find all DNA errors that may be relevant for treating metastatic cancer. This is because actionable DNA errors remain remarkably stable over time, despite ...
Aug 9, 2021
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Whole-genome sequencing analysis of cutaneous T-cell lymphomas has revealed that deletions of the gene PD1 were associated with worse prognoses, according to a recent Northwestern Medicine study published in Blood.
Aug 5, 2021
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