Neuroscience

Settling the debate on serotonin's role in sleep

Serotonin is a multipurpose molecule found throughout the brain, playing a role in memory, cognition, and feelings of happiness and other emotions. In particular, researchers have long debated serotonin's role in sleep: Does ...

Neuroscience

Serotonin boosts neuronal powerplants protecting against stress

Mitochondria in neurons are the powerhouses that generate energy to execute cellular functions and regulate neuronal survival under conditions of stress. Collaborative research by Prof. Vidita Vaidya and Prof. Ullas Kolthur-Seetharam ...

Psychology & Psychiatry

When neurons are out of shape, antidepressants may not work

Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medication for major depressive disorder (MDD), yet scientists still do not understand why the treatment does not work in nearly thirty percent ...

Neuroscience

A new map of the brain's serotonin system

As Liqun Luo was writing his introductory textbook on neuroscience in 2012, he found himself in a quandary. He needed to include a section about a vital system in the brain controlled by the chemical messenger serotonin, ...

Psychology & Psychiatry

Serotonin speeds learning

An international team from the Champalimaud Centre for the Unknown (CCU), in Portugal, and the University College London (UCL) in the U.K. has uncovered a previously unknown effect of serotonin on learning. Their results ...

Psychology & Psychiatry

Mutation links bipolar disorder to mitochondrial disease

Mutations in the gene ANT1 may confer a risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. These two pathways have been separately implicated in bipolar disorder, ...

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