Medical research

Scientists aim to learn how serotonin modulates behavior

In popular experience the story of how serotonin modulates the brain might seem simple: pop an antidepressant, serotonin levels go up, mood improves. But neuroscientists acknowledge how little they know about how the neurotransmitter ...

Neuroscience

Why stress doesn't always cause depression

Rats susceptible to anhedonia, a core symptom of depression, possess more serotonin neurons after being exposed to chronic stress, but the effect can be reversed through amygdala activation, according to new research in the ...

Neuroscience

Settling the debate on serotonin's role in sleep

Serotonin is a multipurpose molecule found throughout the brain, playing a role in memory, cognition, and feelings of happiness and other emotions. In particular, researchers have long debated serotonin's role in sleep: Does ...

Neuroscience

Serotonin boosts neuronal powerplants protecting against stress

Mitochondria in neurons are the powerhouses that generate energy to execute cellular functions and regulate neuronal survival under conditions of stress. Collaborative research by Prof. Vidita Vaidya and Prof. Ullas Kolthur-Seetharam ...

Psychology & Psychiatry

When neurons are out of shape, antidepressants may not work

Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medication for major depressive disorder (MDD), yet scientists still do not understand why the treatment does not work in nearly thirty percent ...

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