Medical research

Federal policy to reduce deaths from sepsis was mostly ineffective

The first large-scale, multi-hospital evaluation of an "all or none" federal policy intended to improve outcomes in sepsis patients finds that the guidelines are a wash—on average they neither helped nor hurt despite significant ...

Immunology

When body clock runs down, immune system takes time off

It's been said that timing is everything, and that may be particularly true when it comes to the ability to fight off disease. New research published by Cell Press in the February issue of the journal Immunity shows that ...

Diseases, Conditions, Syndromes

Ringer's acetate better for patients with severe sepsis

(HealthDay) -- Fluid resuscitation with hydroxyethyl starch (HES) 130/0.4 for patients with severe sepsis leads to an increased risk of death at day 90 and an increased likelihood of requiring renal-replacement therapy, compared ...

Health

Big data model improves prediction of key hospital outcome

More than half of hospital deaths in the United States are related to severe infections, or sepsis. Yale researchers developed a prediction model, drawing on "big data" about local patients and using machine-learning methods, ...

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