Genetics

New taxonomy of non-skeletal rare disorders with impact on bone

Thanks to major progress in the understanding and management of rare congenital diseases and syndromes, many patients with these rare disorders are now living longer lives. With this progress it has become apparent that many ...

Diseases, Conditions, Syndromes

Gut microbiome translates stress into sickle cell crises

A new study shows how chronic psychological stress leads to painful vessel-clogging episodes—the most common complication of sickle-cell disease (SCD) and a frequent cause of hospitalizations. The findings, made in mice, ...

Addiction

Cannabis shows potential for mitigating sickle cell disease pain

Cannabis appears to be a safe and potentially effective treatment for the chronic pain that afflicts people with sickle cell disease, according to a new clinical trial co-led by University of California, Irvine researcher ...

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