Medical research

Using base editing to treat sickle cell disease in mice

A team of researchers from the Broad Institute, Harvard University and St. Jude Children's Research Hospital has used a base editing technique in a novel way to treat sickle cell disease (SCD) in mice. In their paper published ...

Genetics

Using advanced imaging to study sickle cell disease

Sickle Cell Disease (SCD) is a genetically inherited group of red blood cell disorders. According to the CDC, an estimated 90,000 to 100,000 people in the United States live with this disease, and it disproportionately affects ...

Diseases, Conditions, Syndromes

COVID-19: Who's at higher risk of serious symptoms?

Over a year into the COVID-19 pandemic, it's important to remind people who is more at risk of serious coronavirus disease 2019 (COVID-19) symptoms, which can vary widely. Some people have no symptoms at all, while others ...

Neuroscience

Neuroscientist discusses using CRISPR to accelerate brain research

The gene editing technique CRISPR has been making headlines worldwide for its potential to change the genetic makeup of organisms and treat genetic diseases such as sickle cell anemia. It has vast potential in many areas—including ...

Medical research

Base editors flex sights on sickle-cell disease

Researchers at Beam Therapeutics have developed a redesigned base editor that shows considerable promise in directly repairing the single-base mutation that causes sickle-cell disease (SCD). Many strategies are being pursued ...

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