Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor. The discovery offers a promising new treatment target for a cancer that is always fatal.
Jul 14, 2020
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Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently ...
Jul 8, 2020
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Scientists at LMU have shown that a signaling pathway that is disrupted in Ewing sarcoma specifically sensitizes tumor cells to a particular drug. The finding may open a route to new therapies for the most aggressive forms ...
May 18, 2020
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Researchers at the Research Center for Natural Sciences and other institutes in Hungary have recently carried out a study investigating the involvement of brain regions other than the amygdala—more specifically, the lateral ...
Researchers have published a new study that suggests a signaling pathway called ROBO2 is a therapeutic target for kidney diseases, specifically kidney podocyte injury and glomerular diseases.
May 4, 2020
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Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal pathway develop head and neck cancer over an extremely short period of ...
Mar 25, 2020
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An important biological mechanism that is thought to protect brain cells from neurodegenerative diseases such as Alzheimer's and Parkinson's may also be involved in regulating sleep, according to new research from the Perelman ...
Mar 12, 2020
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By studying the sick hearts removed from four patients undergoing heart transplants, researchers have identified a protein and a signaling pathway that may contribute to sudden death in an inherited form of heart disease.
Mar 3, 2020
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Plexin-B2, an axon guidance protein in the central nervous system (CNS), plays an important role in wound healing and neural repair following spinal cord injury (SCI), according to research conducted at the Icahn School of ...
Mar 2, 2020
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Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as "leaky gut"—in which microbes and other molecules seep out of the intestines—may be more common, and more harmful, than previously ...
Feb 10, 2020
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