Patients with cancers driven by the protein KRAS, which are particularly hard to treat, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex, according to results presented ...
Oct 20, 2013
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Children born with developmental disorders called cohesinopathies can suffer severe consequences, including intellectual disabilities, limb shortening, craniofacial anomalies, and slowed growth. Researchers know which mutations ...
Oct 3, 2013
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For many years, patients with advanced thyroid cancer faced bleak prospects and no viable treatment options. But now, building on recent discoveries about the genetics and cell signaling pathways of thyroid tumors, researchers ...
Sep 28, 2013
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Like normal cells, cancer cells require amino acids for growth, maintenance, and cell signaling, and L-type amino acid transporters (LATs) are the delivery vehicles that supply them. Metastatic, castration-resistant prostate ...
Sep 19, 2013
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Scientists have succeeded in growing stem cells that have the ability to develop into two different types of cells that make up a healthy pancreas. The research team led by Dr. Hans Clevers of the Hubrecht Institute, The ...
Sep 17, 2013
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Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found a group of proteins essential to the formation of long-term memories.
Sep 12, 2013
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During formation of the vascular system, successively smaller blood vessels sprout from existing ones to form networks of capillaries in patterns uniquely adapted to the function of the organ they enter. This process, called ...
Aug 30, 2013
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Researchers at the Medical College of Wisconsin (MCW) have developed a new bioinformatics software tool designed to more easily identify genetic mutations responsible for cancers. The tool, called DrGaP, is the subject of ...
Aug 26, 2013
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By studying the planarian flatworm, a master of regenerating missing tissue and repairing wounds, Whitehead Institute Member Peter Reddien and his lab have identified an unexpected source of position instruction: the muscle ...
Aug 15, 2013
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In what is the biggest study of its kind to date, researchers from Technische Universität München (TUM) have identified over 10,000 different proteins in cancer cells. "Nearly all anti-tumor drugs are targeted against cellular ...
Aug 8, 2013
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