Gerontology & Geriatrics
DNAmFitAge: Biological age indicator incorporating physical fitness
A new research paper titled "DNAmFitAge: biological age indicator incorporating physical fitness" has been published in Aging.
Jun 7, 2023
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Page 40 - News tagged with signal pathways
Genetics
Age-related methylation changes in the human sperm epigenome
A new research paper titled "Age-related methylation changes in the human sperm epigenome" has been published in Aging.
Mar 21, 2023
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Oncology & Cancer
Therapeutic resistance linked to softer tissue environment in breast cancer
Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen matrix that surrounds the ...
Apr 2, 2021
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Medical research
Researchers find the pathway responsible for taste changes among chemotherapy patients
Many patients undergoing chemotherapy experience severe taste disruptions that make eating a challenge at a time when maintaining good nutrition is extremely important. Because the type of chemotherapy drugs used varies among ...
Mar 3, 2015
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Medical research
New blood: Tracing the beginnings of hematopoietic stem cells
Hematopoietic stem cells (HSCs) give rise to all other blood cell types, but their development and how their fate is determined has long remained a mystery. In a paper published online this week in Nature, researchers at ...
Aug 14, 2014
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Medical research
In regenerating planarians, muscle cells provide more than heavy lifting
By studying the planarian flatworm, a master of regenerating missing tissue and repairing wounds, Whitehead Institute Member Peter Reddien and his lab have identified an unexpected source of position instruction: the muscle ...
Aug 15, 2013
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Oncology & Cancer
New insights made into cellular signalling pathway linked to cancer and other diseases
Researchers at McMaster University have learned more about the regulation of a cellular signalling pathway involved in the development of several types of cancer, including colon cancer.
Sep 12, 2017
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Oncology & Cancer
New idea for targeting the common cancer protein KRAS
Patients with cancers driven by the protein KRAS, which are particularly hard to treat, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex, according to results presented ...
Oct 20, 2013
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Oncology & Cancer
Researchers use new molecular inhibitors to successfully hit difficult cancer target
Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer.
Feb 5, 2013
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Medical research
Experimental compound extends life in amyotrophic lateral sclerosis mouse model
UT Southwestern Medical Center researchers have identified an experimental molecular compound that improved survival among cellular models and mouse models of amyotrophic lateral sclerosis (ALS), the fatal neurodegenerative ...
Feb 6, 2024
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