Oncology & Cancer
Molecular basis underlying colorectal cancer revealed
A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.
Sep 15, 2020
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Page 9 - News tagged with signal pathways
Oncology & Cancer
Researchers find potential to make brain cancers in children respond better to treatment
Brain cancer in children is always a devastating diagnosis, but McMaster University researchers may have found a way to have the most serious types of pediatric brain cancer respond better to therapies.
Aug 28, 2020
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Medical research
New type of taste cell discovered in taste buds
Our mouths may be home to a newly discovered set of multi-tasking taste cells that—unlike most known taste cells, which detect individual tastes—are capable of detecting sour, sweet, bitter and umami stimuli. A research ...
Aug 13, 2020
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Oncology & Cancer
Scientists ID gene responsible for deadly glioblastoma
Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor. The discovery offers a promising new treatment target for a cancer that is always fatal.
Jul 14, 2020
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Oncology & Cancer
A helping hand for cancer immunotherapy
Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently ...
Jul 8, 2020
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Medical research
Exploiting a signaling pathway disruption that sensitizes tumor cells to a particular drug
Scientists at LMU have shown that a signaling pathway that is disrupted in Ewing sarcoma specifically sensitizes tumor cells to a particular drug. The finding may open a route to new therapies for the most aggressive forms ...
May 18, 2020
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Neuroscience
Protective brain-cell housekeeping mechanism may also regulate sleep
An important biological mechanism that is thought to protect brain cells from neurodegenerative diseases such as Alzheimer's and Parkinson's may also be involved in regulating sleep, according to new research from the Perelman ...
Mar 12, 2020
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Medical research
Human gut-in-a-dish model helps define 'leaky gut,' and outline a pathway to treatment
Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as "leaky gut"—in which microbes and other molecules seep out of the intestines—may be more common, and more harmful, than previously ...
Feb 10, 2020
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Oncology & Cancer
How the immune system becomes blind to cancer cells
T cells play a huge role in our immune system's fight against modified cells in the body that can develop into cancer. Phagocytes and B cells identify changes in these cells and activate the T cells, which then start a full-blown ...
Jan 31, 2020
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Psychology & Psychiatry
Scientists develop new method that predicts vulnerability to stress
Stress is part of life for everyone, but how we respond to it seems to vary from person to person. For some, the effects of a stressful situation can be long-lasting and lead to anxiety, depression, and other health problems; ...
Dec 17, 2019
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