Medical research

Charting the SH2 pool

New research published in BioMed Central's open access journal Cell Communication and Signaling describes a large set of interactions (interactome) which maps the range of phosphotyrosine (pTyr)-dependent interactions with ...

Neuroscience

Video shows the traffic inside a brain cell

Using bioluminescent proteins from a jellyfish, a team of scientists has lit up the inside of a neuron, capturing spectacular video footage that shows the movement of proteins throughout the cell.

Oncology & Cancer

A new target in acute myeloid leukemia

Acute myeloid leukemia, a common leukemia in adults, is characterized by aberrant proliferation of cancerous bone marrow cells. Activating mutations in a protein receptor known as FLT3 receptor are among the most prevalent ...

Oncology & Cancer

How tumor cells create their own pathways

Metastasis occurs when tumor cells "migrate" to other organs through the bloodstream. Scientists have now discovered the trick tumor cells use to invade tissue from the blood vessels: They produce signaling proteins to make ...

Oncology & Cancer

Enzyme offers new therapeutic target for cancer drugs

Researchers at the University of California, San Diego School of Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process that allows a single ...

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