Gerontology & Geriatrics
DNAmFitAge: Biological age indicator incorporating physical fitness
A new research paper titled "DNAmFitAge: biological age indicator incorporating physical fitness" has been published in Aging.
Jun 7, 2023
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Page 27 - News tagged with signaling
Neuroscience
How synaptic vesicles accumulate glutamate
In the brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, ...
Jun 6, 2023
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Neuroscience
Study: Stress granules control Alzheimer's gene transcripts and neuronal proteostasis
A new research paper was published on the cover of Aging, title "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."
Jun 1, 2023
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Medications
Studying the body's opioid system could reduce side effects of opioid drugs
Opioid drugs such as morphine and fentanyl are like the two-faced Roman god Janus: The kindly face delivers pain relief to millions of sufferers, while the grim face drives an opioid abuse and overdose crisis that claimed ...
May 31, 2023
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Neuroscience
Discovery of a neuronal microcircuit in the fruit fly's complex symphony of vision
An orchestra of complex neuronal networks performs a symphonic masterpiece called vision—an exciting field for neurobiologists like Alexander Borst, director at the Max Planck Institute for Biological Intelligence. In his ...
May 31, 2023
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Neuroscience
Chronic pain can be objectively measured using brain signals—new research
Using a brain implant that can record neural signals over many months, my research team and I have discovered objective biomarkers of chronic pain severity in four patients with chronic pain as they went about their daily ...
May 27, 2023
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Oncology & Cancer
Colon cancer: Curcumin activates tumor suppressive signaling pathway
Colorectal cancer is one of the most common types of cancer worldwide. In more than half of all cases, an important protective mechanism in cells is inactivated by mutations—the tumor suppressor gene p53. The product of ...
May 25, 2023
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Genetics
Study: External factors shape genetic predisposition to lipids, Alzheimer's and heart disease in MLXIPL gene
A new research paper titled "Exogenous exposures shape genetic predisposition to lipids, Alzheimer's, and coronary heart disease in the MLXIPL gene locus" has been published in Aging.
May 24, 2023
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Genetics
Researchers target protein that can slow down muscular dystrophy
A team of researchers at the University of Houston College of Pharmacy is reporting that by manipulating TAK1, a signaling protein that plays an important role in development of the immune system, they can slow down disease ...
May 24, 2023
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Immunology
The aging mouse prostate: Kinetics of lymphocyte infiltration
A new research paper titled "Highly multiplexed immune profiling throughout adulthood reveals kinetics of lymphocyte infiltration in the aging mouse prostate" has been published in Aging.
May 23, 2023
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