Using a new approach for studying live embryonic mouse brains at single-cell resolution, researchers have identified an active multi-layer circuit that forms in the cortex during an unexpectedly early stage of development. ...
Apr 17, 2023
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A new technique reported in Science this week overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in ...
Dec 5, 2019
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With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting. Most of the focus has been on developing genetic sequencing assays or analyses ...
Apr 18, 2024
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University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes ...
Dec 12, 2023
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Headaches such as migraine are among the leading causes of morbidity worldwide, but most treatments provide only partial relief. While scientists know that migraine and related headaches are caused by activity in a part of ...
Mar 28, 2022
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A new animal model developed by Massachusetts General Hospital (MGH) investigators promises to be less expensive, easier to use and to improve personalized therapies for cancers and potentially other diseases. In their paper ...
Apr 25, 2019
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For the first time, researchers examine the effects of gender-affirming androgen therapy on breast tissue in transgender men with single-cell resolution. Their results give an unprecedented look into the changes that occur ...
Mar 8, 2023
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When one travels through rough terrain, maps come in handy. They also help researchers to study the complex organization of the brain. Scientists at the Max Planck Institute for Biological Intelligence have created a new ...
Feb 22, 2023
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A team led by investigators at Weill Cornell Medicine and NewYork-Presbyterian has used advanced technology and analytics to map, at single-cell resolution, the cellular landscape of diseased lung tissue in severe COVID-19 ...
Mar 29, 2021
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A study published in Science reports a comprehensive database of single-neuron projectomes consisting of over 10,000 mouse hippocampal neurons, thus revealing the spatial connectivity patterns of mouse hippocampal neurons ...
Feb 1, 2024
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