Diabetes

The skeletal muscle inflammation enigma

Exercise is associated with skeletal muscle inflammation, yet physical activity has beneficial effects on type 2 diabetes (T2D). Recent EU research has looked at the molecules that result in this contradiction.

Overweight & Obesity

A new way to target high rates of obesity

A novel drug is being touted as a major step forward in the battle against Australia's escalating rates of obesity and associated metabolic diseases. As it stands, 2 in 3 adults in Australia are classified as being overweight ...

Medical research

Leptin hormone spurs body's shift from burning carbs to fat

To keep the human brain supplied with energy when food was scarce, mammals evolved the ability to switch from burning carbohydrates to burning fat in order to preserve skeletal muscle that would otherwise be metabolized and ...

Health

Menopause and estrogen affect muscle function

According to a study conducted at the University of Jyväskylä, estrogen acts as a regulator of muscle energy metabolism and muscle cell viability. Menopause leads to the cessation of ovarian estrogen production concurrent ...

Medical research

Exercise-induced hormone irisin is not a 'myth'

Irisin, a hormone linked to the positive benefits of exercise, was recently questioned to exist in humans. Two recent studies pointed to possible flaws in the methods used to identify irisin, with commercially available antibodies. ...

Diabetes

Exercise-induced capillary density ups insulin sensitivity

(HealthDay)—Exercise training is associated with an increase in skeletal muscle capillary density (CD), which contributes to improvements in glucose metabolism, according to a study published online June 11 in Diabetes.

Genetics

Long-term endurance training impacts muscle epigenetics

A new study from Karolinska Institutet in Sweden shows that long-term endurance training in a stable way alters the epigenetic pattern in the human skeletal muscle. The research team behind the study, which is being published ...

Diabetes

Androgen receptor signaling tied to insulin resistance

(HealthDay)—Mouse models show tissue-specific androgen receptor (AR) signaling is involved in regulation of metabolism, which may explain the link between androgen deprivation therapy (ADT) and the development of metabolic ...

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