What drives tumor growth? Is it a few rogue cells imposing their will upon healthy tissue, or diseased tissue bringing out the worst in otherwise peaceable cells? Or is it a back-and-forth, a dialogue between the two? According ...
Nov 30, 2022
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Melanopsin (OPN4) is a light-sensing protein found in skin and retina cells. A new study conducted at the University of São Paulo (USP) in Brazil suggests that OPN4 can also participate in the development and progression ...
Aug 9, 2022
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A team of Yale-led researchers can now quantify the factors causing changes in the DNA that contribute most to cancer growth in tumors of most major tumor types.
Apr 27, 2022
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New research in Advanced NanoBiomed Research indicates that testing an individual's blood can reveal the presence of circulating melanoma cells. Such tests may allow patients to forego invasive skin biopsies to determine ...
Apr 20, 2022
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Many melanoma patients are treated with drugs called BRAF or MEK inhibitors that specifically target the mutant proteins created in cancerous tumors. These inhibitors can block the tumors' ability to grow and spread.
Feb 28, 2022
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Immune checkpoint inhibitors, which strengthen the immune response against tumor cells, have become standard of care for many patients with advanced cancers; however, the medications can often cause side effects, most commonly ...
Jan 12, 2022
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Mutations of the gene MLL4 in epithelial skin cells can inhibit healthy cell turnover and may lead to keratinocyte cancers, which collectively outnumber all other human cancers. Targeting pathways altered by MLL4 mutations ...
Dec 21, 2021
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About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds ...
Nov 19, 2021
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Leonard Harris, assistant professor of biomedical engineering, led a team of researchers from Vanderbilt University that has shown how an in vitro model of tumor heterogeneity, or diversity, resolves three different sources ...
Jul 15, 2021
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Immune checkpoint inhibitors, which boost the immune system's response against tumor cells, have transformed treatment for many advanced cancers, but short-term clinical trials and small observational studies have linked ...
Apr 12, 2021
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