Oncology & Cancer
Study identifies causes of cancer
A team of Yale-led researchers can now quantify the factors causing changes in the DNA that contribute most to cancer growth in tumors of most major tumor types.
Apr 27, 2022
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News tagged with skin tumors
Oncology & Cancer
Discovering a potential explanation for treatment resistance in skin cancer
Many melanoma patients are treated with drugs called BRAF or MEK inhibitors that specifically target the mutant proteins created in cancerous tumors. These inhibitors can block the tumors' ability to grow and spread.
Feb 28, 2022
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Oncology & Cancer
Researchers find new potential targets for skin cancer treatment
Mutations of the gene MLL4 in epithelial skin cells can inhibit healthy cell turnover and may lead to keratinocyte cancers, which collectively outnumber all other human cancers. Targeting pathways altered by MLL4 mutations ...
Dec 21, 2021
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Immunology
Suffering from psoriasis? Blame this trio of proteins
About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds ...
Nov 19, 2021
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Oncology & Cancer
Non-genetic tumor diversity contributes to treatment failure in cancer patients
Leonard Harris, assistant professor of biomedical engineering, led a team of researchers from Vanderbilt University that has shown how an in vitro model of tumor heterogeneity, or diversity, resolves three different sources ...
Jul 15, 2021
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Oncology & Cancer
Researchers find cellular evidence behind lasting immune response in some cancer survivors
Some melanoma patients respond very well to immunotherapy, experiencing profound and durable tumor regression. A fraction of these patients will also develop autoimmunity against their normal melanocytes—the cells that ...
Mar 24, 2021
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176
Medical research
Researchers develop injection to treat skin cancer
Yale researchers are developing a skin cancer treatment that involves injecting nanoparticles into the tumor, killing cancer cells with a two-pronged approach, as a potential alternative to surgery.
Feb 2, 2021
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Oncology & Cancer
Controlling CAR T cells with light selectively destroys skin tumors in mice
Bioengineers at the University of California San Diego have developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed ...
Feb 19, 2020
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Oncology & Cancer
Shape-shifting stem cells are key to cancer metastasis and immune evasion
Just as people tend to become stuck in their ways as they grow older so too do cells. Neurons in the brain don't one day decide to become heart cells; skin cells repair wounds with skin cells rather than kidney cells.
Feb 11, 2020
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Oncology & Cancer
Whole-genome study of metastatic tumors provides a catalog of genetic features of metastatic cancer
A team of researchers with members affiliated with multiple institutions in The Netherlands and Australia has conducted the largest-ever whole-genome study of metastatic solid tumors. In their paper published in the journal ...
