A team led by scientists from the Trinity Biomedical Sciences Institute (TBSI) has unearthed the possible target for treating the debilitating skin disease hidradenitis suppurativa (HS), which is a painful, chronic, inflammatory ...
Sep 26, 2023
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University of Queensland researchers have identified a novel drug target with the potential to overcome drug resistance and prevent tumor regrowth in cancer patients.
Sep 21, 2023
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New research in the June 2023 issue of Journal of the National Comprehensive Cancer Network has found that when alectinib—a safe and effective small molecule kinase inhibitor used to treat some types of advanced lung cancer—was ...
Jun 12, 2023
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A new research perspective titled "Using cancer proteomics data to identify gene candidates for therapeutic targeting" has been published in Oncotarget.
May 10, 2023
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Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma—a lethal ...
Dec 5, 2022
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A combination therapy pairing a small molecule inhibitor with monoclonal antibody immunotherapy improved patient outcomes for relapsed chronic lymphocytic leukemia (CLL), according to a Northwestern Medicine clinical trial ...
Aug 2, 2021
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In a study published in Nature Metabolism, researchers at the department of Cell and Molecular Biology developed a novel technique to identify small molecules that can make insulin-producing β-cells divide.
May 26, 2021
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A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study ...
Apr 2, 2021
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A study led by researchers at Baylor College of Medicine reveals a novel role of the steroid receptor coactivator 3 (SRC-3/NCOA3), a protein crucial for steroid hormone function and a prognostic marker for aggressive human ...
Feb 11, 2021
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Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that ...
Dec 17, 2020
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