Cardiology

New target found for treating thoracic aortic aneurysm

It's a silent, sudden and almost assured killer: a thoracic aortic aneurysm (TAA) occurs when a weak spot or bulge in the body's main pipeline for pumping blood suddenly ruptures, cutting off the supply of life-sustaining ...

Cardiology

RNA modification is important factor in smooth muscle contraction

Genetic information is stored in DNA and is passed on in a very stable manner from one cell to the next or from one generation to the next. On a cellular level, genetic information is transcribed from DNA into RNA (ribonucleic ...

Immunology

Key to artery health lies in LYVE-1 macrophage

Arteries such as the aorta actively transport oxygenated blood, nutrients and cells throughout the body to keep our tissues functioning normally. Damage to the arteries can result in life-threatening cardiovascular diseases. ...

Immunology

Chemotherapy-induced diarrhea traced to immune cells

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening. Their problems occur when contractions in the smooth muscle lining the ...

Neuroscience

'Second brain' neurons keep colon moving

Millions of neurons in the gastrointestinal tract coordinate their activity to generate the muscle contractions that propel waste through the last leg of the digestive system, according to a study of isolated mouse colons ...

Cardiology

Study examines the rise of plaque in arteries

The accumulation of cholesterol plaques in artery walls can lead to atherosclerosis, or the hardening of arteries that contributes to heart attacks and strokes. In a new study, Yale researchers investigate how plaque cells ...

Medical research

Crosstalk between cells plays role in pulmonary hypertension

Pulmonary hypertension is a type of high blood pressure that affects blood vessels in the lungs. Once diagnosed, patients have limited treatment options, and many do not live beyond seven years. In a new study, scientists ...

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