The lab of Stephen Waxman, Bridget M. Flaherty Professor of Neurology and of Neuroscience, has identified the key role of sodium channels arrayed on nerve cells in experience of pain.
Oct 24, 2019
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Finnish researchers have found cellular components in the epithelial tissue of the eye, which have previously been thought to only be present in electrically active tissues, such as those in nerves and the heart. A study ...
Aug 15, 2019
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Mutations in small proteins that help convey electrical signals throughout the body may have a surprisingly large effect on health, according to results of a new Johns Hopkins study study published in Proceedings of the National ...
Jan 6, 2014
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Dravet syndrome (DS) is a form of infantile-onset, treatment-resistant epilepsy that is caused by a mutation in the gene encoding a voltage-gated sodium channel, SCN1A. DS patients have a 30-fold increased risk of dying from ...
Mar 25, 2013
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Patients with irregular heartbeats, or arrhythmia, have few effective treatment options—available drugs are not always effective, and an implanted defibrillator can be too aggressive.
Oct 29, 2019
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Researchers at NYU Langone Medical Center have developed the first large animal model of an inherited arrhythmic syndrome - an advance that will lead to a better understanding of the biologic mechanisms important in normal ...
Dec 15, 2014
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Important brain structures that are key for signaling in the brain are narrower and less dense in females, and more likely to be damaged by brain injuries, such as concussion. Long-term cognitive deficits occur when the signals ...
May 13, 2024
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Sodium channels in the cells that line the tiny capillaries in our lungs play an important role in keeping those capillaries from leaking and potentially worsening conditions like pneumonia, scientists report.
Sep 5, 2017
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Induced pluripotent stem cells (iPScs) from the skin of patients with Dravet syndrome (DS) show Dravet-like functional impairment when they are converted into neurons, finds research in BioMed Central's open access journal ...
May 1, 2013
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New research led by a scientist at the University of York reveals that a process that forms a key element in the development of the nervous system may also play a pivotal role in the spread of breast cancer.
Apr 24, 2014
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