In laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route—catastrophic macropinocytosis.
Dec 18, 2019
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Today, a team of investigators at Children's Hospital Los Angeles launched OncoKidsSM, a next-generation sequencing-based panel specifically designed for pediatric cancers. OncoKids is intended to guide the diagnosis and ...
Jun 21, 2017
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Inflammation, cell division and cell differentiation that occur during skeletal muscle regeneration may provide an ideal environment for the highly malignant tumor, rhabdomyosarcoma to arise. These are the findings from a ...
Feb 22, 2012
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In children with rhabdomyosarcoma, or RMS, a rare cancer that affects the muscles and other soft tissues, the presence of mutations in several genes, including TP53, MYOD1, and CDKN2A, appear to be associated with a more ...
Jun 24, 2021
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The DASPO-group for data analysis and survival for personalized oncology has developed an app that provides dynamic predictions of survival for patients suffering from soft tissue sarcoma. Patients with soft tissue sarcoma ...
Jan 22, 2020
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A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs)—soft tissue tumors that are stubbornly resistant to chemotherapy and radiation—according to a laboratory study ...
Jan 31, 2024
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Using novel machine learning tools developed at Stanford Medicine, researchers have mapped three distinct cellular configurations that correspond to clinical outcomes for patients with a rare, difficult-to-treat cancer called ...
Mar 27, 2024
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Patients undergoing spinal fusion surgery with bone morphogenetic protein (BMP) appear to be at increased risk of benign tumors—but not cancers, reports a study in the September issue of Neurosurgery, official journal of ...
Sep 6, 2013
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Among the deadliest cancers is a rare malignancy called mesenchymal chondrosarcoma, which begins in cartilage around bones and typically strikes young adults.
May 12, 2015
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We all learned in school that the beams from X-ray machines pass right through soft tissues like skin and internal organs, but not dense materials like bones, right? Not so fast.
Mar 31, 2020
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