An investigational cancer drug that targets tumors caused by mutations in the KRAS gene will be evaluated in phase 2 clinical trials, following promising safety and efficacy results in preliminary human studies and excellent ...
Dec 23, 2019
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191
Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, have published a new study explaining how they took a protein once thought to be too challenging for targeted ...
Aug 1, 2023
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200
During infection or tumor growth, a type of specialized white blood cells called CD8+ T cells rapidly multiply within the spleen and lymph nodes and acquire the ability to kill diseased cells. Some of these killer T cells ...
Dec 11, 2017
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861
The emerging field of synthetic biology—designing new biological components and systems—is revolutionizing medicine. Through the genetic programming of living cells, researchers are creating engineered systems that intelligently ...
Jul 3, 2019
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6
Most skin cancer drugs that activate the immune system work by triggering immune cells, called T cells, to attack tumors, but when T cells are activated for too long, they can wear out and cease to function. A new study led ...
Jun 15, 2022
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156
A preclinical study led by scientists at the UCLA Jonsson Comprehensive Cancer suggests that heating solid tumors during CAR T-cell therapy can enhance the treatment's success.
Mar 27, 2019
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11
A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and bladder, that have ...
Apr 11, 2021
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152
A collaborative project to bring the promise of cell therapy to patients with a deadly form of brain cancer has shown dramatic results among the first patients to receive the novel treatment. In a paper published in the New ...
Mar 13, 2024
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164
Johns Hopkins Medicine researchers have revamped an anti-cancer drug to better target cancer cells and leave healthy tissues unharmed. Scientists have dubbed this type of targeted approach a "prodrug"—a medicine designed ...
Nov 16, 2022
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1583
By silencing the molecular pathway that prevents macrophages from attacking our own cells, University of Pennsylvania engineers have manipulated these white blood cells to eliminate solid tumors.
Jun 12, 2023
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574
