Genetics
DNA changes accelerate body's aging process
DNA changes throughout a person's life can significantly increase their susceptibility to heart conditions and other age-related diseases, research suggests.
Sep 2, 2019
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Page 7 - News tagged with somatic mutation
Neuroscience
Accurate detection of low-level somatic mutation in intractable epilepsy
KAIST medical scientists have developed an advanced method for perfectly detecting low-level somatic mutation in patients with intractable epilepsy. Their study showed that deep sequencing replicates of major focal epilepsy ...
Aug 14, 2019
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Genetics
Deciphering brain somatic mutations associated with Alzheimer's disease
Researchers have identified somatic mutations in the brain that could contribute to the development of Alzheimer's disease (AD). Their findings were published in the journal Nature Communications last week.
Jul 18, 2019
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Genetics
Identifying the risk of recurrence of developmental disorder in future pregnancies
Having a child with a developmental disorder can cause parents to worry about the outcome of further pregnancies. In cases where the genetic mutation causing the disorder is not present in either parent, it is assumed to ...
Jun 17, 2019
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Oncology & Cancer
Researchers show that mutations in human livers can promote tissue regeneration
Researchers at the Children's Medical Center Research Institute at UT Southwestern (CRI) have identified genetic mutations that accumulate in the adult liver that can promote regeneration in the context of chronic liver damage.
Apr 4, 2019
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Medical research
Natural gene therapy for intractable skin disease discovered
Pathogenic gene mutations causing a type of intractable skin disease can be eliminated from some parts of patients' skin as they age, according to Hokkaido University researchers and their collaborators in Japan. This represents ...
Apr 1, 2019
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Genetics
Editing genes shouldn't be too scary—unless they are the ones that get passed to future generations
Gene editing is one of the scarier things in the science news, but not all gene editing is the same. It matters whether researchers edit "somatic" cells or "germline" cells.
Mar 18, 2019
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Oncology & Cancer
Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children
St. Jude Children's Research Hospital scientists have identified genetic variations in a fourth gene that are associated with an increased risk of acute lymphoblastic leukemia (ALL) in Hispanic children. The research appears ...
Feb 14, 2019
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Genetics
PGDx machine learning approach outperforms existing mutation detection methods in study
Personal Genome Diagnostics today announced that its machine learning-based technology, CerebroTM, outperforms existing methods to identify tumor-specific or somatic mutations, enabling more accurate NGS clinical test results. ...
Sep 5, 2018
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Medical research
Researchers characterize 'mutational burden' of human induced pluripotent stem cells
The therapeutic potential of human induced pluripotent stem cells (iPSCs), which are capable of becoming almost any type of cell in the human body, is well-recognized and broadly pursued, but their mutational burden has not ...
Jul 24, 2018
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