Immunology

New insights into the control of inflammation

Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of pro-inflammatory genes in macrophages. ...

Neuroscience

Scientists paint multi-color atlas of the brain

The human brain contains approximately 86 billion neurons, or nerve cells, woven together by an estimated 100 trillion connections, or synapses. Each cell has a role that helps us to move muscles, process our environment, ...

Neuroscience

Brainstem neurons control both behaviour and misbehaviour

A recent study at the University of Helsinki reveals how gene control mechanisms define the identity of developing neurons in the brainstem. The researchers also showed that a failure in differentiation of the brainstem neurons ...

Diseases, Conditions, Syndromes

Cognitive disorders linked to severe COVID-19 risk

Dementia and other cognitive disorders now appear to be risk factors for developing severe COVID-19, according to research from the University of Georgia. The findings highlight the need for special care for populations with ...

Obstetrics & gynaecology

Researchers zero in on genetic connection to postpartum hemorrhage

Researchers have identified genetic mutations that appear to protect women from severe bleeding after childbirth, a leading cause of maternal death. A preliminary study of the findings is being presented at the ANESTHESIOLOGY ...

Genetics

Biological sex affects genes for body fat, cancer, birth weight

Biological sex has a small but ubiquitous influence on gene expression in almost every type of human tissue, reports a new study from Northwestern Medicine, the University of Chicago and the Centre for Genomic Regulation ...

Diseases, Conditions, Syndromes

'Hotspots' of a SARS-CoV-2 infection in the human body

An infection with the coronavirus SARS-CoV-2 can affect multiple organs. With this in mind, researchers of the German Center for Neurodegenerative Diseases (DZNE) and Cornell University in the US have investigated cellular ...

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