Medications

One step closer to chronic pain relief

Sortilin, which is a protein expressed on the surface of nerve cells, plays a crucial role in pain development in laboratory mice—and in all likelihood in humans as well. This is the main conclusion of the study "Sortilin ...

Medications

FDA approves $2M medicine, most expensive ever

U.S. regulators have approved the most expensive medicine ever, for a rare disorder that destroys a baby's muscle control and kills nearly all of those with the most common type of the disease within a couple of years.

Neuroscience

In lab, researchers flip pain switch in spinal cord cells

Facing an urgent need for safer and more effective therapies for those suffering from debilitating pain in the midst of an opioid crisis, Saint Louis University researchers are on a mission to find a non-narcotic off-switch ...

Neuroscience

The GPS of neurons now better understood

Our nerves consist of small cables responsible for circulating information to every part of our body, allowing us, for instance, to move. These cables are actually cells called neurons with long extensions named axons.

Neuroscience

Like mountaineers, nerves need expert guidance to find their way

Similar to the dozens of Sherpas that guide hikers up treacherous Himalayan mountains to reach a summit, the nervous system relies on elaborate timing and location of guidance cues for neuronal axons—threadlike projections—to ...

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